论文部分内容阅读
目的:分析异甘草酸镁治疗药物性肝炎患者的临床疗效及安全性。方法:100例在本院就诊的因使用抗结核药物导致肝功能损害的患者,分成观察组和对照组。对照组给予甘草酸单铵,观察组给予异甘草酸镁。结果:观察组总有效率为80.00%,明显优于对照组总有效率48.00%,差异显著(P<0.01)。治疗后观察组谷丙转氨酶(ALT)、总胆红素(STB)改善明显优于对照组,差异显著(P<0.01)。结论:应用异甘草酸镁治疗抗结核药物所致药物性肝损害患者疗效可靠,具有良好的安全性。
Objective: To analyze the clinical efficacy and safety of magnesium isoglycyrrhizinate in the treatment of patients with drug-induced hepatitis. Methods: One hundred patients treated in our hospital were divided into two groups: observation group and control group. The control group was given monoammonium glycyrrhizinate. The observation group was given magnesium glycyrrhizinate. Results: The total effective rate in the observation group was 80.00%, which was significantly better than that in the control group (48.00%). The difference was significant (P <0.01). After treatment, the improvement of alanine aminotransferase (ALT) and total bilirubin (STB) in the observation group was significantly better than that in the control group (P <0.01). Conclusion: The application of magnesium isoglycyrrhizinate in the treatment of patients with drug-induced liver damage caused by anti-TB drugs is reliable and has good safety.