人乳头瘤病毒(human papillomavirus,HPV)是一个拥有一百多种亚型的大家族,分布在人体很多部位的皮肤和黏膜,男性和女性都有,最常见的是口咽部、肛门和生殖道。HPV分为高危型和低危型,持续的高危型病毒感染是导致宫颈鳞癌及其癌前病变的最重要的致病因素,几乎所有(>99.9%)病变中都有高危型HPV感染。大部分口咽部肿瘤(63%) Human papillomavirus (HPV) is a large family of more than one hundred subtypes that are found in many parts of the human body, skin and mucous membranes, both men and women, the most common being the oropharyngeal, anal and reproductive Road. HPV is divided into high-risk and low-risk types. Persistent high-risk virus infection is the most important causative factor leading to cervical squamous cell carcinoma and its precancerous lesions. Almost all (> 99.9%) lesions have high-risk HPV infection. Most oropharyngeal tumors (63%)