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目的探讨以静脉血栓栓塞(TVE)为首发表现的肺癌临床特点,及其对肺癌诊断的意义。方法回顾性分析2009年-2012年期间以VTE为首发表现的6例肺癌患者的临床资料,均以上、下肢深静脉血栓形成收住院,其中合并肺栓塞2例。均在住院或随访期间诊断肺癌,其中腺癌5例,小细胞癌1例。结果随访期间4例1年内死亡,2例存活。结论临床遇及原发性静脉血栓形成患者应积极寻找病因,对抗凝治疗效果不佳者要警惕恶性肿瘤,及时完善肿瘤相关检查,以早期诊治。
Objective To investigate the clinical features of lung cancer with venous thromboembolism (TVE) as the first manifestation and its significance in the diagnosis of lung cancer. Methods The clinical data of 6 patients with lung cancer with VTE as the first manifestation during 2009-2012 were retrospectively analyzed. All patients were admitted to the hospital with deep venous thrombosis of upper and lower extremities, including 2 cases of pulmonary embolism. Lung cancer was diagnosed during hospitalization or follow-up, including 5 cases of adenocarcinoma and 1 case of small cell carcinoma. Results During the follow-up period, 4 patients died within 1 year and 2 patients survived. Conclusions Patients with clinical and primary venous thrombosis should actively look for the cause, to anticancer treatment ineffective to be alert to malignant tumors, promptly improve the tumor-related tests to early diagnosis and treatment.