目前妇科良性肿瘤(如子宫肌瘤、卵巢囊肿、畸胎瘤等)的发病率在中青年妇女中逐年上升,这种手术多采用腹腔镜肿瘤剔除或子宫全切术进行治疗。但是这个年龄段的患者情绪易波动,手术疼痛及外周环境干扰使其产生术后失眠(睡眠剥夺现象),从而导致身体不适感影响其医疗舒适度[1]。因此,如何使其正常生理功能尽快恢复、提高患者围术期的医疗舒适感是医患双方均迫切想解决的问题。研究表明,帕瑞昔布钠具有较强的镇痛作用,而围手术期应用该药是否能改善患者术后舒适度 The current incidence of benign gynecological tumors (such as uterine fibroids, ovarian cysts, teratomas, etc.) in the incidence of young women increased year by year, the use of laparoscopic resection of the tumor or hysterectomy for treatment. However, patients in this age group are prone to fluctuate in their emotions and suffer from postoperative insomnia (sleep deprivation) due to surgical pain and peripheral environmental interference, which may lead to discomfort affecting their medical comfort [1]. Therefore, how to restore normal physiological functions as soon as possible and improve the medical comfort during perioperative period are the urgent problems to be solved by both doctors and patients. Studies have shown that parecoxib sodium has a strong analgesic effect, and perioperative application of the drug can improve postoperative comfort