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冠状动脉临界病变在冠状动脉病变中占比例大.部分临界病变容易导致急性心血管事件,但将所有的临界病变都进行支架置入治疗又增加了手术并发症,容易过度治疗.冠状动脉临界病变的治疗策略是介入治疗的一难点,需结合患者临床表现、心肌缺血情况、病变血管供血范围、病变特点综合决策.血流储备分数、光学相干断层成像等检查能帮助了解病变的血流动力学信息和病变血管长度、狭窄程度、斑块性质等解剖学特点,指导冠状动脉临界病变的治疗策略,现就血流储备分数、光学相干断层成像对冠状动脉临界病变治疗策略的指导作用做一综述.“,”Intermediate coronary artery lesions account for a large proportion of coronary artery disease .Partial intermediate coronary artery lesions can easily lead to acute cardiovascular events.However, all intermediate coronary artery lesions are treated with stent implantation,which increases surgical complications and is prone to overtreatment.The treatment strategy of intermediate coronary artery lesions is a difficult point in interventional therapy.It is necessary to make a comprehensive decision based on clinical manifestations , myocardial ischemic conditions ,blood supply range of diseased vessels ,and the characteristics of vascular lesion.Fractional flow reserve and optical coherence tomography can help us understand the hemodynamic information and lesion length ,degree of stenosis,characteristics of plaque and other anatomical features ,so as to guide the treatment strategy of the intermediate coronary artery lesions .This paper is a review to elucidate the role of fractional flow reserve and optical coherence tomography for patients with the intermediate coronary artery lesions .