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目的:观察热敏灸对老年骨质疏松症患者的骨密度(BMD)及血清骨钙素(BGP)表达的影响。方法:将62例患者随机分为热敏灸组及药物组,分别以敏感穴位热灸法治疗、阿伦膦酸钠内服对照。观察症状体征、BMD测定、BGP测定结果变化。结果:2组治疗前各部位BMD测定值比较,差异均无显著性意义(P>0.05);治疗3月后,热敏灸组的各区BMD较治疗前均有明显增加,差异均有显著性意义(P<0.05);药物组各区BMD治疗前后也有轻微变化,但差异均无显著性意义(P>0.05),2组治疗后比较,各区BMD值差异均有显著性或非常显著性意义(P<0.05,P<0.01)。2组治疗前血清BGP含量比较,差异无显著性意义(P>0.05)。治疗3月后,2组BGP较治疗前均有不同程度降低,与治疗前比较,差异均有非常显著性意义(P<0.01),且治疗后热敏灸组BGP比药物组降低更明显(P<0.05)。治疗3月后,2组显效率比较,差异有显著性意义(P<0.05),热敏灸组疗效优于药物组。结论:热敏灸可增加骨密度、改善临床症状。
Objective: To observe the effects of heat-sensitive moxibustion on bone mineral density (BMD) and serum osteocalcin (BGP) in elderly patients with osteoporosis. Methods: Sixty-two patients were randomly divided into heat-sensitive moxibustion group and drug group. The patients were treated with hot moxibustion at acupoint points of sensitivity and oral alendronate orally. Symptoms and signs observed, BMD test, BGP test results change. Results: There was no significant difference between the two groups before treatment (P> 0.05). After 3 months of treatment, the BMD in each area of the heat-sensitive moxibustion group increased significantly compared with that before treatment, with significant difference (P <0.05). There was also a slight change before and after treatment of BMD in each group in the drug group, but there was no significant difference between the two groups (P> 0.05). After treatment, the difference of BMD in each group was significant or very significant P <0.05, P <0.01). There was no significant difference in serum BGP levels between the two groups before treatment (P> 0.05). After 3 months of treatment, BGP in both groups decreased to some extent compared with that before treatment, and the difference was significant (P <0.01) compared with that before treatment, and the BGP in heat-sensitive moxibustion group was more obvious than that in drug group P <0.05). After 3 months of treatment, the effective rates of the two groups were significantly different (P <0.05), and the effects of the heat-sensitive moxibustion group were better than those of the drug group. Conclusion: Thermal moxibustion can increase bone mineral density and improve clinical symptoms.