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目的分析肛周脓肿患者脓液培养病原菌及药敏实验结果,并探讨合并糖尿病组与未合并糖尿病组患者在脓肿培养阳性率、主要致病菌的种类、主要抗生素的耐药性等方面的差异。方法将脓液接种于培养瓶中,置BACT/ALERT3D培养仪中培养,采用Vitek-2 Compact全自动微生物鉴定仪对细菌进行鉴定及药敏试验。结果合并糖尿病组培养阳性率为48.6%,未合并糖尿病患者为69.9%,2组间差异有统计学意义(P<0.05);脓肿培养主要病原菌是大肠埃希菌和肺炎克雷伯菌,2种菌的检出率在2组患者中差异有统计学意义(P<0.05);大肠埃希菌ESBLs携带率及氨苄西林、复方新诺明、头孢曲松、左旋氧氟沙星、头孢吡肟耐药率在2组患者间差异有统计学意义(P<0.05)。结论 2组患者在培养阳性率、病原菌分布、抗生素耐药率等方面差异均有统计学意义。
Objective To analyze the pathogenic bacteria and drug susceptibility test results of pus culture in patients with perianal abscess and to explore the differences in the positive rate of abscess culture, the types of main pathogenic bacteria and the main antibiotic resistance in patients with and without diabetes mellitus . Methods The pus was inoculated into culture flasks and cultured in a BACT / ALERT3D culture instrument. The bacteria were identified and drug susceptibility test by Vitek-2 Compact automatic microbial identification instrument. Results The positive rate of culture in combination group was 48.6% and that in non-combined group was 69.9%. There was significant difference between the two groups (P <0.05). The main pathogenic bacteria of abscess were Escherichia coli and Klebsiella pneumoniae 2 The detection rate of the inoculum was significantly different between the two groups (P <0.05). The carrier rate of Escherichia coli ESBLs, ampicillin, cotrimoxazole, ceftriaxone, levofloxacin, The rate of oxime resistance in the two groups was significantly different (P <0.05). Conclusion The two groups of patients in culture positive rate, distribution of pathogens, antibiotic resistance rates and other differences were statistically significant.