A Study on Protein Residue Contacts Prediction by Recurrent Neural Network

来源 :仿生工程学报(英文版) | 被引量 : 0次 | 上传用户:wxthaoa
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
A new method was described for using a recurrent neural network with bias units to predict contact maps in proteins.The main inputs to the neural network include residues pairwise, residue classification according to hydrophobicity, polar,acidic, basic and secondary structure information and residue separation between two residues. In our work, a dataset was used which was composed of 53 globulin proteins of known 3D structure. An average predictive accuracy of 0. 29 was obtained. Our results demonstrate the viability of the approach for predicting contact maps.
其他文献
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7
Human embryonic stem (hES) cells provide a promising supply of specific cell types for transplantation therapy. We presented here the method to induce different
OsNHX1 gene (Na+/H+ antiporter gene of Oryza sativa L.) was introduced into Poplar 84K with Agrobacterium tumefaciens-mediated transformation. PCR, Southern and
The human pescadillo gene encodes a protein with a BRCT domain. Pescadillo plays an important role in DNA synthesis, cell proliferation and transformation. Sinc
本文通过对荣华二采区10
Microtubule and microfilament cytoskeletons play key roles in the whole process of cytokinesis. Although a number of hypotheses have been proposed to elucidate
The mitochondrial 16S ribosomal RNA gene is sequenced from 24 ingroups taxa, including 18 species from Labeoninae grouped in 13 genera. Phylogenetic analyses ar
To investigate the role of SH-2-containing protein tyrosine phosphatase 1, SHP-1, in IL-4-induced IL-4 receptor (IL-4R) expression, we examined IL-4 receptor α
A gene encoding the trehalose phosphorylase (TreP), which reversibly catalyzes trehalose degradation and synthesis from a-glucose-1-phosphate (α-GIc-1-P) and g
Age structure of a plant population carries important information on population dynamics. The traditional age classification of individuals by development phase