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目的:正常人体细胞经过一定数目的分裂后,端粒(telomere)逐渐缩短,最后进入一种不分裂状态,也称衰老(senescence)状态。端粒酶(telomerase)是一种反转录酶,它用自身模板合成端粒重复序列(TTAGGG)n,使端粒维持一定的长度,细?
OBJECTIVE: After a certain number of divisions of normal human cells, telomeres gradually shorten and finally enter a state of non-split, also called senescence. Telomerase is a reverse transcriptase that uses its own template to synthesize telomere repeat sequence (TTAGGG)n to maintain a certain length of telomeres.