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目的 :研究滋心阴胶囊 ,对麻醉大鼠血流动力学的影响。方法 :测定十二指肠注射滋心阴胶囊剂影响麻醉大鼠动脉收缩压 (SAP)、舒张压 (DAP)、左室内收缩峰值压 (LVSP)。结果 :其下降程度为LVSP >DAP >SAP。在心率不变的同时伴有 +dp/dtmax、Vmax的降低 ,这表明滋心阴胶囊剂可能通过负性肌力作用来降低心肌耗氧量。结论 :滋心阴胶囊能缓解冠心病心绞痛、心肌梗塞时供氧和需氧的失衡。
Objective : To study the effect of Zixinyin Capsule on the hemodynamics of anesthetized rats. METHODS: The duodenal injection of Zi Xinyin Capsule was used to determine the arterial systolic pressure (SAP), diastolic pressure (DAP), and left ventricular systolic pressure (LVSP) in anesthetized rats. Result: The degree of decline was LVSP>DAP>SAP. In the same heart rate, there is a decrease in +dp/dtmax and Vmax, indicating that Zixinyin capsule may reduce myocardial oxygen consumption through negative inotropic effect. Conclusion: Zixinyin capsule can relieve the imbalance of oxygen supply and aerobic in angina pectoris and myocardial infarction.