获得性免疫缺陷综合征(AIDS)是一种主要影响男性同性恋人群的严重免疫性疾病,常伴有机会性全身感染、中枢神经系统感染和少见的全身性肿瘤。本文报导2例脑部原发性淋巴瘤伴有AIDS。例1,40岁同性恋男性,患弥漫性卡波西氏(Kaposi)肉瘤伴肺部复发性细菌感染,用CT扫描鉴别昏迷原因。于邻近右侧脑室前角处有阴影增深病灶。按经验用磺胺嘧啶和乙胺嘧啶作弓形体病治疗17天,但该病灶的体积不变。在轻度血小板减少症的情况下作针刺活检,并发了致命性大脑内出血。活检证实大脑组织被形态一致的单核细胞中度浸润,为典型的大脑 Acquired Immunodeficiency Syndrome (AIDS) is a severe immune disease that affects male homosexuals. It is often accompanied by opportunistic systemic infections, central nervous system infections, and rare systemic tumors. This article reports two cases of primary brain lymphoma with AIDS. Case 1, 40-year-old homosexual men with diffuse Kaposi’s sarcoma with recurrent bacterial infection of the lungs, CT scans to identify the cause of coma. There are shadow-deepened lesions in the anterior horn of the adjacent right ventricle. According to experience, sulfadiazine and pyrimethamine were used to treat toxoplasmosis for 17 days, but the volume of the lesion remained unchanged. Acupuncture biopsy with mild thrombocytopenia complicated fatal intracerebral hemorrhage. Biopsy confirms that brain tissue is moderately infiltrated by unimorphically mononuclear cells, a typical brain