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目的：探讨地市级妇幼保健机构高危儿综合管理模式及效果。方法以2012年1月~2014年1月本院儿童保健门诊专案管理的1403例高危儿为研究组，以2012年前2年本院儿童保健门诊系统管理的1394例高危儿为对照组。研究组实施综合管理模式，对照组实施常规管理模式。对比分析两组患儿管理效果。结果研究组各项指标均优于对照组，<0.05；早产、低出生体重、窒息或缺氧缺血性脑病等为随访至1岁、2岁高危儿的常见高危因素。结论综合管理模式在地市级妇幼保健机构高危儿管理中发挥着重要的作用，能提升高危儿随访率和早期干预效果，值得进行深入研究和推广。“,”Objective To investigate the municipal maternal and child health care institutions high-risk infants integrated management mode and effect.Methods In January 2012-January 2014 in our hospital project management of 1403 cases of high-risk infants child care clinics for the team,2 years to 2012 years ago in our hospital outpatient service system in child care management of 1394 cases of high-risk infants as control group.Team to implement comprehensive management mode, control group routine management mode.Analysis of two groups of children with management effect. Results The team all the indexes were superior to control group, <0.05;Premature birth,low birth weight,asphyxia or hypoxia ischemic encephalopathy aged for follow-up to 1,2,a common risk factors of high-risk infants.Conclusion Comprehensive management mode in municipal maternal and child health care institutions play an important role in management of high-risk infants,can increase the rate of high-risk infants follow-up and early intervention effect,worthy of in-depth research and extension.