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目的分析阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与老年高血压的相关性。方法 OSAHS老年高血压患者205例均行24 h动态血压监测及夜间多导睡眠图(PSG)监测。根据呼吸暂停低通气指数(AHI)分为4组,非OSAHS高血压组40例、轻度OSAHS高血压组50例、中度OSAHS高血压组60例、重度OSAHS高血压组55例,比较4组临床特征、血压指标、睡眠指标,分析OSASH与老年高血压相关性。结果轻、中、重度OSAHS高血压组24 hSBP、24 hDBP、dSBP、dDBP及nSBP、nDBP水平均高于非OSAHS高血压组,且重度OSAHS高血压组血压高于轻度OSAHS高血压组,OSAHS病情程度与血压水平呈正相关(P<0.05);24 hSBP、24 hDBP、dSBP、dDBP及nSBP、nDBP及身体质量指数与OSAHS发生关系密切。结论 OSASH与老年高血压关系密切,可为临床诊治提供参考。
Objective To analyze the relationship between obstructive sleep apnea-hypopnea syndrome (OSAHS) and senile hypertension. Methods Twenty-five ambulatory blood pressure monitoring and nighttime polysomnography (PSG) monitoring in 205 OSAHS elderly hypertensive patients were performed. According to the apnea hypopnea index (AHI), the patients were divided into four groups: 40 patients in non-OSAHS hypertensive group, 50 patients in mild OSAHS hypertensive group, 60 patients in moderate OSAHS hypertensive group and 55 patients in severe OSAHS hypertensive group. Group clinical features, blood pressure indicators, sleep indicators, OSASH and elderly hypertension analysis. Results The levels of 24 h DBP, 24 d DBP, 24 d DBP, d DBP, n SBP and nDBP in mild, moderate and severe OSAHS patients were higher than those in non-OSAHS hypertension patients and those in patients with severe OSAHS hypertension were higher than those in patients with mild OSAHS hypertension and OSAHS The severity of illness was positively correlated with the blood pressure (P <0.05). The 24 h SBP, 24 h DBP, dSBP, dDBP and nSBP, nDBP and body mass index were closely related to OSAHS. Conclusion OSASH is closely related to elderly hypertension, which may provide a reference for clinical diagnosis and treatment.