血管内皮生长因子 (VEGF)是血管生成的主要促进因子之一 ,参与多种伴有血管增生的生理与病理过程。例如妇女生殖周期和妊娠过程、伤口愈合过程、增殖型糖尿病视网膜病变、缺血性心肌病、类风湿关节滑膜炎、Graves综合征等。由于实体肿瘤的生长与转移和肿瘤血管新生密切相关 ,例 Vascular endothelial growth factor (VEGF) is one of the major promoters of angiogenesis, involved in a variety of physiological and pathological processes associated with vascular proliferation. Such as women’s reproductive cycle and pregnancy process, wound healing process, proliferative diabetic retinopathy, ischemic cardiomyopathy, rheumatoid arthritis synovitis, Graves syndrome. As solid tumor growth and metastasis and tumor angiogenesis are closely related, for example