1955年有人研究静脉内应用透明质酸酶能够减轻急性心肌梗塞时心脏的损害,以后又证明了静脉内应用透明质酸酶能明显地降低S—T升高。他们还证明冠状动脉闭塞后应用透明质酸酶,24小时测量局部缺血损害减轻,进一步研究证明冠状动脉结扎后6小时应用此药,对缺血心肌仍有保护作用。冠状动脉结扎的时间和注射 In 1955 was studied intravenous hyaluronidase can reduce cardiac damage in acute myocardial infarction, and later proved that intravenous hyaluronidase can significantly reduce the S-T increased. They also demonstrated that hyaluronidase was applied after coronary artery occlusion and that ischemic damage was reduced at 24 hours. Further studies demonstrated that administration of this drug 6 hours after coronary ligation had protective effects on ischemic myocardium. Coronary ligation time and injection