Injectable hydrogel wound dressing based on strontium ion cross-linked starch

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Severe skin wounds cause great problems and sufferings to patients.In this study,an injectable wound dressing based on strontium ion cross-linked starch hydrogel (SSH) was developed and evaluated.The good inject-ability of SSH made it easy to be delivered onto the wound surface.The good tissue adhesiveness of SSH ensured a firm protection of the wound.Besides,SSH supported the proliferation of NIH/3T3 fibroblasts and facilitated the migration of human umbilical vein endothelial cells (HUVECs).Importantly,SSH exhibited strong antibacterial effects on Staphylococcus aureus (S.aureus),which could prevent wound infection.These results demonstrate that SSH is a promising wound dressing material for promoting wound healing.
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