稚泻停颗粒可明显降低正常大鼠胃肠推进功能。对豚鼠离体回肠的收缩活动有抑制作用,呈剂量依赖性;并能拮抗及消除新斯的明引起的肠管运动兴奋。十二指肠给药能明显抑制家兔在体肠管的运动,并能拮抗由新斯的明和磷酸组胺引起的肠管运动亢进。灌胃给药,对利血平诱发大鼠腹泻有较好的止泻作用。此外,该药对二甲苯所致的小鼠耳壳肿胀有一定的抑制作用。体外试验表明,对常见肠道细菌有较广泛的抑菌作用,但所需浓度较高。 Kidney granules can significantly reduce the gastrointestinal propulsion function of normal rats. It inhibited the contractile activity of isolated guinea pig ileum in a dose-dependent manner, and it could antagonize and eliminate the excitatory movement of the intestine caused by neostigmine. Duodenal administration can significantly inhibit the movement of rabbit intestine intestine and can antagonize the intestinal hyperkinesis caused by neostigmine and histamine phosphate. Gavage administration had better antidiarrheal effect on reserpine-induced diarrhea in rats. In addition, the drug has a certain inhibitory effect on the swelling of the ear shell in mice caused by xylene. In vitro tests have shown that there is a broader bacteriostatic effect on common gut bacteria, but the required concentration is higher.