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【目的】探讨肺热症状与小儿多发性抽动症的发病关系。【方法】采用病例对照研究,将诊断为小儿多发性抽动症的48例设为病例组,另选择同一时期就诊其他疾病的96例设为对照组。调查患者的一般情况、主诉、家族史、发病时肺热症状等因素,对资料进行单因素分析和多因素分析。【结果】单因素分析结果显示:咳嗽、痰黄、咽红肿痛、声嘶等是小儿多发性抽动症的危险因素(P<0.05),相对危险度(OR)分别为2.345、4.405、5.160和11.70。多因素分析结果显示:随着痰黄、咽红肿痛、声嘶等因素的存在,患小儿多发性抽动症的危险增加。而咳嗽在多因素分析中被剔除。【结论】咳嗽、痰黄、咽红肿痛、声嘶等肺热症状与小儿多发性抽动症的发病有关,但仅从病例对照研究还无法确定其之间是否存在因果关系。
【Objective】 To investigate the relationship between Hyperthermia and pediatric multiple Tourette’s disease. 【Methods】 A case-control study was conducted in which 48 cases diagnosed as having multiple twitch syndrome in children were enrolled in the case group. 96 cases of other diseases in the same period were selected as the control group. Investigate the general situation of patients, chief complaint, family history, incidence of Hyperactivity and other factors, the data were univariate and multivariate analysis. [Results] The results of univariate analysis showed that cough, phlegm yellow, sore throat, hoarseness were the risk factors for children with multiple tic disorder (P <0.05), and the relative risk was 2.345, 4.405 and 5.160 respectively And 11.70. Multivariate analysis showed that: With the presence of phlegm yellow, sore throat, hoarseness and other factors, the risk of children with Tourette increased. Cough was excluded from multivariate analysis. 【Conclusion】 Cough, phlegm yellow, sore throat, hoarseness and other symptoms of Hyperthermia are related to the pathogenesis of multiple twitch syndrome in children. However, it is impossible to determine the causal relationship between them only from the case-control study.