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BACKGROUND AND OBJECTIVE:To correlate structure and function in eyes with end-stage glaucoma.PATIENTS AND METHODS:Fifty six eyes of 48 patients with glaucoma presenting with end-stage glaucoma underwent scanning laser polarimetry(SLP) imaging using a commercially available GDx-variable corneal compensator unit(GDx-VCC;Laser Diagnostics Technologies,Inc.,San Diego,CA) .End-stage glaucoma was defined by both disc appearance and standard automated perimetry visual field criteria.Standard automated perimetry parameters included:mean deviation,pattern standard deviation,and total deviation plot.GDx parameters included:TSNIT average,superior average,inferior average,TSNIT standard deviation,and nerve fiber indicator.RESULTS:The visual field mean deviation was 26.75 ± 3.50 dB.The remaining retinal nerve fiber layer measured in this group of eyes was:TSNIT average,29.76± 5.81 μ m;superior average,30.76± 6.25 μ m;and inferior average,31.14± 7.20 μ m.A low structure-function correlation was found when analyzing separately the superior and inferior hemifields(R2=0.000 01,R2=0.001 6,respectively) .CONCLUSIONS:In eyes with end-stage glaucoma,very thin but existing retinal nerve fiber layer is found on SLP.Such values rarely dropped below 10 to 20 μ m.A flattening of the GDx TSNIT pattern was seen,and the correlation between structure and function was not evident.
BACKGROUND AND OBJECTIVE: To correlate structure and function in eyes with end-stage glaucoma. PATIENTS AND METHODS: Fifty six eyes of 48 patients with glaucoma presenting with end-stage glaucoma underwent scanning laser polarimetry (SLP) imaging using a commercially available GDx-variable End-stage glaucoma was defined by both disc appearance and standard automated perimetry visual field criteria. Last automated perimetry parameters included: mean deviation, pattern standard deviation, and total deviation plot. GDD parameters included: TSNIT average, superior average, inferior average, TSNIT standard deviation, and nerve fiber indicator. RESULTS: The visual field mean deviation was 26.75 ± 3.50 dB. this group of eyes was: TSNIT average, 29.76 ± 5.81 μm; superior average, 30.76 ± 6.25 μm; and inferior average, 31.14 ± 7.20 μ mA low structure-function correlation w as found when analyzing separately the superior and inferior hemifields (R2 = 0.000 01, R2 = 0.001 6, respectively) .CONCLUSIONS: In eyes with end-stage glaucoma, very thin but existing retinal nerve fiber layer is found on SLP. The following is a form of the GDx TSNIT pattern was seen, and the correlation between the structure and function was not evident.