系统性红斑狼疮(SLE)男性患者少见,本文对收治的45例进行分析。45例男性SLE占同期住院SLE患者总数的10.5％;发病年龄4～55岁,平均23岁,诊断年龄5～59岁,平均26岁;死亡共6例,占7.5％,分别在确诊后1～6年内死于尿毒症3例,狼疮脑病2例,感染性休克1例。半数以上临床表现为发热(39/45)、肾病(39/45)、关节痛(26/45)、面部红斑(25/45),其次常见的表现有皮肤斑丘疹、肝大及神经精神病。实验室检查常见血小板减少和贫血。肾病、神 Systemic lupus erythematosus (SLE) male patients rare, this article 45 cases were analyzed. 45 cases of male SLE accounted for 10.5% of the total number of hospitalized SLE patients in the same period; the age of onset was from 4 to 55 years with an average of 23 years old, the diagnosis was from 5 to 59 years old, with an average of 26 years; 6 cases died, accounting for 7.5% 6 cases died of uremia in 3 cases, 2 cases of lupus encephalopathy and 1 case of septic shock. More than half of the clinical manifestations were fever (39/45), nephropathy (39/45), joint pain (26/45), facial erythema (25/45), followed by common manifestations of cutaneous rash, hepatomegaly and neuropsychiatric disorders. Laboratory tests common thrombocytopenia and anemia. Kidney disease, God