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目的探究改良腹腔镜保守手术与米非司酮联合治疗输卵管妊娠的临床效果。方法选取漯河市第三人民医院2014年10月—2015年9月收治的84例输卵管妊娠患者,依据治疗方法不同分为常规组与研究组,各42例。常规组应用常规腹腔镜保守手术治疗,研究组予以改良腹腔镜保守手术与米非司酮联合治疗。观察比较两组患者手术时间、术中出血量、术后留院观察时间、术后血HCG(人绒毛膜促性腺激素)下降及术后患侧输卵管阻塞情况。结果与常规组相比,研究组手术时间及术后留院观察时间较短,术中出血量较少,差异有统计学意义(P<0.05);两组患者术后2周内血HCG转阴率相比,研究组97.62%明显高于常规组80.95%,差异有统计学意义(P<0.05);两组患者术后患侧输卵管阻塞发生率相比,差异无统计学意义(P>0.05)。结论改良腹腔镜保守手术与米非司酮联合应用于输卵管妊娠治疗中,可明显降低术中出血量、显著缩短手术时间及术后留院观察时间,有效提高术后血HCG转阴率,确保术后输卵管通畅度。
Objective To investigate the clinical effect of modified laparoscopic conservative surgery combined with mifepristone in the treatment of tubal pregnancy. Methods 84 patients with tubal pregnancy admitted to the Third People’s Hospital of Luohe from October 2014 to September 2015 were divided into the routine group and the study group according to the different treatment methods, 42 cases in each group. Conventional laparoscopic conservative surgery routine treatment group, the study group to be modified laparoscopic conservative surgery and mifepristone combination therapy. The operation time, intraoperative blood loss, postoperative stay observation time, postoperative blood HCG (human chorionic gonadotropin) decline and postoperative tubal obstruction were compared between the two groups. Results Compared with the conventional group, the operation time of the study group and the time of postoperative stay in hospital were shorter, and the amount of bleeding during the operation was less, the difference was statistically significant (P <0.05). In the two groups, 97.62% in the study group was significantly higher than that in the conventional group (80.95%, P <0.05). There was no significant difference in the incidence of tubal obstruction after operation between the two groups (P> 0.05). Conclusion The modified laparoscopic conservative operation combined with mifepristone in the treatment of tubal pregnancy can significantly reduce intraoperative blood loss, significantly shorten the operation time and postoperative hospital stay observation time, effectively improve postoperative blood HCG negative rate, ensure Tubal patency.