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目的探讨冠心病(CHD)合并2型糖尿病患者的临床及冠状动脉的病变特点。方法从冠状动脉造影病例中选取102例(其中冠心病合并2型糖尿病62例,单纯冠心病40例)进行临床表现、血生化和造影结果分析。结果与单纯冠心病组比较,冠心病合并2型糖尿病者有多种心血管危险因素:高血压、血脂异常等(甘油三酯水平高,载脂蛋白A水平低);冠脉血管受累程度高且弥漫性血管病变多,左室射血分数低。结论合并2型糖尿病与不合并2型糖尿病的冠心病患者的冠状动脉造影表现的差异有统计学意义,前者冠状动脉病变更加广泛和严重,左室射血分数更低。
Objective To investigate the clinical characteristics and coronary artery lesions in patients with coronary heart disease (CHD) complicated with type 2 diabetes mellitus. Methods 102 cases of coronary angiography (including 62 cases of coronary heart disease complicated with type 2 diabetes mellitus and 40 cases of simple coronary heart disease) were selected for clinical manifestation, blood biochemistry and imaging analysis. Results Compared with simple coronary heart disease group, there were many cardiovascular risk factors in patients with coronary heart disease and type 2 diabetes mellitus: hypertension and dyslipidemia (high triglyceride level and low apolipoprotein A level); coronary artery involvement was high And more diffuse vascular lesions, low left ventricular ejection fraction. Conclusions There is significant difference in coronary angiography between patients with type 2 diabetes mellitus and those with type 2 diabetes mellitus. The former has more extensive and severe coronary artery disease and lower left ventricular ejection fraction.