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目的探讨2型糖尿病血清超敏C反应蛋白(hs-CRP)与血脂联合检测的相互关系及意义。方法测定65例2型糖尿病患者、60例冠心病患者、54例2型糖尿病并发冠心病患者和80例健康者血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和hs-CRP水平。结果各疾病组hs-CRP水平及血脂各项均比健康对照组高,各疾病组HDL-C比健康对照组低,差异有统计学意义(P<0.05)。结论 hs-CRP作为一个炎症因子,在预测糖尿病及其并发心血管疾病中具有重要的临床意义。
Objective To investigate the relationship between serum hs-CRP and serum lipids in type 2 diabetes mellitus (T2DM) and its significance. Methods Sixty-five patients with type 2 diabetes mellitus, 60 patients with coronary heart disease, 54 patients with type 2 diabetes mellitus complicated with coronary heart disease and 80 healthy subjects were enrolled in this study. Serum total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol and hs -CRP level. Results The levels of hs-CRP and the levels of serum lipids in each disease group were higher than those in healthy control group. The HDL-C in each disease group was lower than that in healthy control group (P <0.05). Conclusion As an inflammatory factor, hs-CRP has important clinical significance in the prediction of diabetes mellitus and its associated cardiovascular diseases.