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目的评价经阴道三维(3D)彩色多普勒超声测定子宫内膜的形态、厚度、容积、内膜及内膜下血流指数预测子宫内膜容受性对选择冻胚解冻移植(FET)时机的作用。方法对110例行FET的患者移植日子宫内膜的形态、厚度、容积、内膜及内膜下血流分型及血流指数进行经阴道三维超声测定。根据临床妊娠与否分为两组,比较上述指标在两组之间有无差异。结果 110例患者中临床妊娠44例,临床妊娠率为40%,妊娠组与未妊娠组间虽子宫内膜的厚度、容积差异无统计学意义(P>0.05),但子宫内膜容积<2.0ml的4例患者,无一例妊娠。妊娠组与未妊娠组间子宫内膜形态、内膜及内膜下血流分型差异有统计学意义(P<0.05),妊娠组子宫内膜S/D、PI、RI低于未妊娠组,差异有统计学意义(P<0.05)。结论通过阴道三维彩色多普勒超声测定子宫内膜形态、容积、内膜及内膜下血流分型、血流动力学参数可以预测子宫内膜容受性,对临床选择FET移植时机有指导价值。
Objective To evaluate the effect of endometrial receptivity on the endometrial morphology, thickness, volume, intima and subintimal blood flow index (VAS) by transvaginal three dimensional (3D) color Doppler ultrasound Role. Methods Transvaginal three-dimensional ultrasound was used to determine the morphology, thickness, volume, intima and subintimal blood flow pattern and blood flow index of 110 patients undergoing FET implantation. According to clinical pregnancy or not divided into two groups, comparing the above indicators in the two groups have no difference. Results The clinical pregnancy rate was 44% in 110 patients and the pregnancy rate was 40%. There was no significant difference in the thickness and volume of endometrium between pregnancy group and non-pregnancy group (P> 0.05), but the endometrial volume was less than 2.0 ml of 4 patients, no case of pregnancy. There was significant difference in the type of endometrium, endometrial and subintimal blood flow between pregnant group and non-pregnant group (P <0.05). The endometrial S / D, PI, RI in pregnancy group were lower than those in non-pregnant group , The difference was statistically significant (P <0.05). Conclusions The endometrial morphology, volume, intima and subintimal blood flow pattern can be determined by vaginal three-dimensional color Doppler ultrasound. Hemodynamic parameters can predict the endometrial receptivity and guide the timing of clinical choice of FET transplantation. value.