综述了近三年人类基因治疗研究的有关进展,认为概念上比传统观点有所拓宽,从而开阔了思路,形成了策略多种和方法多样的局面。在临床上候选的治疗病种日益增多,已从先天性遗传病扩展到后天获得的疾病,如肿瘤等。同时也列举了目前有待解决的问题,指出了光明的前景。 This review summarizes the progress of research on human gene therapy in the past three years and holds that the concept is broaden more than the traditional view, which broadens the thinking and forms a variety of strategies and diverse approaches. Clinically increasing the number of candidates for treatment, has been extended from congenital genetic disease acquired acquired diseases, such as cancer. At the same time, the current problems to be solved are listed and the bright future is pointed out.