1临床资料患者女,45岁。左下肢反复出现皮疹伴疼痛5年余,加重伴右下肢皮疹2个月。近5年来患者的左侧小腿反复出现蚕豆大小的皮下结节,伴触痛,全身不规则发热,皮损局部皮温升高,结节消退后局部皮肤凹陷,弹性消失。当地医院多次行组织病理检查示:结节性发热性非化脓性脂膜炎。2个月前皮疹再次出现,并逐渐增多,右侧小腿和左侧大腿内侧及右侧臀部均出现类似皮疹,多家医院行结核菌素试验、甲状腺功能、血管 1 clinical data Female patient, 45 years old. Left lower extremity recurrence of rashes with pain more than 5 years, increased with right lower extremity rash 2 months. The past five years, the patient’s left leg repeatedly appeared the size of the subcutaneous nodules, with tenderness, irregular body heat, skin lesions increased local temperature, nodular subsided after the local skin depression, elasticity disappears. Multiple histopathological examination showed that the local hospital: nodular fever non-suppurative panniculitis. 2 months ago rash again, and gradually increased, the right leg and left thigh and the right side of the hip were similar rash, a number of hospital tuberculin test, thyroid function, blood vessels