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目的 探讨新的凋亡相关基因TFAR19在系统性红斑狼疮 (SLE)发病机制中的作用 ,及其与SLE病情的关系。方法 利用酶联免疫吸附分析 (ELISA)方法检测TFAR19与SLE患者病情的关系。结果 发现活动期SLE患者血清中TFAR19的抗体值高于稳定期和正常对照组 (P≤0 0 5 )。结论 TFAR19可能和SLE的发病和病情有关
Objective To investigate the role of a novel apoptosis-related gene TFAR19 in the pathogenesis of systemic lupus erythematosus (SLE) and its relationship with SLE. Methods The relationship between TFAR19 and SLE patients was analyzed by enzyme-linked immunosorbent assay (ELISA). The results showed that serum levels of TFAR19 in active SLE patients were higher than those in stable and normal controls (P≤0 05). Conclusion TFAR19 may be related to the pathogenesis and condition of SLE