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用放射自显影术对口腔粘膜鳞状细胞癌癌旁粘膜的细胞动力学研究结果说明,有明显的细胞动力学参数改变的上皮单纯增生可距癌灶较上皮异常增生更远,并可呈跳跃方式存在,应视为癌旁粘膜的危险区,应连同癌组织一并切除。细胞动力学研究有助于手术范围的确定和了解癌旁粘膜中细胞增殖规律以及癌变过程的机理。
The results of cell kinetic studies of paratumor mucosa of oral mucosal squamous cell carcinoma by autoradiography show that epithelial hyperplasia with obvious changes in cell kinetic parameters can be farther from epithelial dysplasia than that of epithelial dysplasia, and can show jumping. The presence of the method should be regarded as a dangerous area of paraneoplastic mucosa and should be removed together with the cancerous tissue. The study of cell dynamics is helpful to determine the scope of surgery and to understand the mechanism of cell proliferation and the mechanism of canceration in paraneoplastic mucosa.