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许多内外因素的变化,常可影响个体对化学毒物的感受性。本文所报导的实验,旨在评价脱水因素可能存在的这种影响。实验分两部分:(1)研究正常和脱水动物注射或接触化学毒物的感受性。根据各个毒物,测定不同的反应项目,包括死亡率、死亡速率、心率的改变以及行为的变化。(2)研究脱水对机体防御化学毒物的三种生理功能的影响:呼吸道粘膜和纤毛的清除作用,肺泡巨噬细胞的作用,以及肝脏微粒体酶对毒的代谢作用。
Many changes in internal and external factors, often can affect the individual’s sensitivity to chemical poisons. The experiments reported in this article aim to assess the possible effects of dehydration. The experiment is divided into two parts: (1) to study the susceptibility of normal and dehydrated animals to injection or exposure to chemical poisons. Depending on the individual poisons, different response items were determined, including mortality, rate of death, changes in heart rate, and changes in behavior. (2) To study the effect of dehydration on the three physiological functions of the body’s defense against chemical toxins: the removal of respiratory mucosa and cilia, the action of alveolar macrophages, and the metabolism of liver microsomal enzymes to the virus.