【摘 要】
：
INTRODUCTION The antitumor activity of norcantharidin (NCTD),the demethylated analogue of cantharidin, was studied in the early 1980s in China. NCTD has no side
【机 构】
：
Liaocheng Teachers University,China-Japan Friendship Institute of Clinical Medical Sciences,Institut
【基金项目】
：
the Educational Committee of Shandong Province
论文部分内容阅读
INTRODUCTION The antitumor activity of norcantharidin (NCTD),the demethylated analogue of cantharidin, was studied in the early 1980s in China. NCTD has no side effects on urinary organs which cantharidin has shown and is easier to synthesize, and it can inhibit the proliferation of several tumor cell lines as well as transplanted tumors. Clinical trials with NCTD as a monotherapeutic agent indicated that NCTD had beneficial effects in patients with different kinds of digestive tract cancers, such as primary hepatoma,carcinomas of esophagus and gastric cancer, but no depressive effect on bone marrow cells. NCTD can increase the white blood cell count by stimulating the bone marrow and has some antagonistic effect against leukopenia caused by other agents. The exact cellular and molecular mechanisms of NCTD on tumor cells have not yet been elucidated to date[1-3].
其他文献
地理学科相比其它学科更重于理性，以说理为主，但一味追求理性的东西，会把课堂变的死气沉沉、枯燥乏味。要让地理教学过程变成一弘活水，必须注入美的情感，渗透审美教育，让学生在接受
The product distribution and gasoline quality of FCC process, especially the olefin content,heavily depends on the catalyst performance in terms of selective/no
The aim of this investigation was to study the effects of fat-soluble extracts from vegetable powder (FEFVP) and β-carotene on the proliferation and apoptosis
从编辑部的角度对如何发挥编委的作用进行分析。通过组建最佳编委会,由编委组织优秀栏目、确定选题,开展多种活动,协助增加收入,借助全国及各地学术会议召开编委会等,我们体
文章在前人研究的基础上,以中日两国的家族企业发展为研究对象,从国家政策环境出发,比较研究了不同的财政、税收、金融政策在家族企业发展过程中对企业发展构成的不同影响.
文中在TI Davinci平台的基础上研究了安全VoIP视频电话终端的设计与实现,通过研究SIP通信中存在的注册劫持、服务器伪装、消息篡改等一系列安全威胁,针对SIP的安全问题改进了
To study the effect of glutamate on the intracellular calcium signal of pure cultured ratastrocytes and the role of NMDA and AMPA receptors in the procedure, th
To investigate the effects of mycophenolate mofetil MMF) on the process of renal inter-stitial fibrosis,unilateral ureteral obstruction (UUO) model was establis
The expression of glucose regulated protein 94 (GRP94)during the treatment of human colorectal carcinoma cell lineClone A cells with sodium butyrate was studied