多发性硬化(ＭＳ)是青年人中最常见的神经纤维脱髓鞘疾病,临床主要表现为两种病程:复发缓解和缓慢进展。应用核磁共振成像(ＭＲＩ)可发现早期ＭＳ患者。但至今不清楚此类人群的临床过程及预后。本文回顾性评估青少年期ＭＳ患者的临床特点及发病过程。方法　共418例患者。青少年 Multiple sclerosis (MS) is the most common neurodegenerative demyelinating disease in young people. The main clinical manifestations are two kinds of disease course: remission and slow progress. Application of magnetic resonance imaging (MRI) can be found in patients with early MS. But so far the clinical course and prognosis of such people are not clear. This article retrospectively evaluates the clinical features and pathogenesis of adolescent MS. Methods A total of 418 patients. teens