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目的对海岛居民前列腺癌患病情况进行分析,讨论其主要危险因素以及不同分级病患术后康复情况。方法选取2012年1月1日至2017年1月1日期间,来我院就诊的前列腺癌病患30例。根据Gleason评分和前列腺特异抗原(PSA)值将病患划分为三组,分别为高危组12例、中危组10例,低危组8例;按照所搜集病患一般资料,对海岛居民前列腺癌患者危险因素进行分析,并对比讨论不同分级患者术后康复情况。结果体质量指数(OR=1.021、P=0.006)、年龄(OR=2.343,P=0.008)、前列腺炎(OR=3.561、P=0.007)均对前列腺癌患者生存质量有较强解释能力,为主要危险因素。前列腺患者的保护因素包括:首次性生活时间(OR=0.776、P=0.003)和首次遗精时间(OR=0.321、P=0.005)。低危组病患预后康复情况较为理想,并预后康复情况和Gleason评分之间呈现出明显的反比例关系。高危组术后复发率为57.63%、中危组术后复发率为27.78%、低危组组术后复发率为13.79%,可明显看出低危组患者复发率相对于高危组和中危组复发率明显偏低(χ~2=6.253、7.142,P<0.01);高危组术后病死率为11.86%、中危组术后病死率为5.56%、低危组组术后病死率为3.45%,可见高危组术后病死率水平明显高于其他两组(χ~2=8.214、7.142,P<0.01)。结论体重质量超标、年龄偏大、前列腺炎是临床上前列腺病患的主要危险因素;而保护因素包括首次性生活时间较晚、首次遗精时间晚。一般情况下,低危组在术后康复情况方面明显优于高危组和中危组病患,而病死率水平则明显低于两组。前列腺分级对海岛居民的前列腺癌临床治疗工作的开展有着重要的积极意义。
Objective To analyze the prevalence of prostate cancer in island residents and discuss the main risk factors and postoperative rehabilitation of patients with different grading. Methods Thirty patients with prostate cancer who came to our hospital from January 1, 2012 to January 1, 2017 were selected. The patients were divided into three groups according to Gleason score and prostate specific antigen (PSA) value: 12 in high-risk group, 10 in intermediate-risk group and 8 in low-risk group. According to the general information of patients collected, Cancer risk factors were analyzed and compared to discuss different levels of postoperative recovery of patients. Results The body mass index (OR = 1.021, P = 0.006), age (OR = 2.343, P = 0.008) and prostatitis (OR = 3.561, P = 0.007) had a strong ability to explain the quality of life of patients with prostate cancer The main risk factors. Prostate patients with protective factors include: first sex life time (OR = 0.776, P = 0.003) and the first spermatorrhea time (OR = 0.321, P = 0.005). The prognosis of patients with low-risk group was better prognosis, and the prognosis of recovery and Gleason score showed a significant inverse relationship between. The recurrence rate was 57.63% in the high-risk group, 27.78% in the middle-risk group, and 13.79% in the low-risk group. The recurrence rate of the low-risk group was obviously higher than that of the high-risk group and intermediate-risk group (Χ ~ 2 = 6.253, 7.142, P <0.01). The postoperative mortality was 11.86% in the high-risk group and 5.56% in the middle-risk group. The mortality rate in the low-risk group was 3.45%, showing that high-risk group postoperative mortality was significantly higher than the other two groups (χ ~ 2 = 8.214,7.142, P <0.01). Conclusions Excessive body weight, older age and prostatitis are the main risk factors in clinical prostatic diseases. The protective factors include late sexual life and late first spermatorrhea. Under normal circumstances, the low-risk group was significantly better than the high-risk group and the moderate-risk group in terms of postoperative recovery, while the mortality rate was significantly lower than the two groups. Prostate grading for island residents in the clinical treatment of prostate cancer has an important positive significance.