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继心得安之后,乙胺碘呋酮(胺碘酮)也显示对心律失常、冠心病、高血压等多种心血管疾病有治疗作用。胺碘酮对血管平滑肌有特异性松弛作用,能扩张冠状动脉和外周动脉,降低冠脉循环阻力和外周血管阻力,且通过α和β肾上腺素能受体的非竞争性抑制而降低儿茶酚胺的交感兴奋作用,故有降压作用,可用于高血压病的治疗。对心脏可减慢静息和运动时的心率,对心肌氧利用率虽无影响,但有抑制交感兴奋
Following the peace of mind, amiodarone (amiodarone) also shows a therapeutic effect on a variety of cardiovascular diseases such as arrhythmia, coronary heart disease and hypertension. Amiodarone has a specific relaxing effect on vascular smooth muscle, which can dilate coronary and peripheral arteries, reduce coronary circulation resistance and peripheral vascular resistance, and reduce sympathetic catecholamines by non-competitive inhibition of alpha and beta adrenergic receptors Excitement, it has antihypertensive effect, can be used for the treatment of hypertension. The heart can slow down the rest and exercise when the heart rate, myocardial oxygen utilization although no effect, but inhibit sympathetic excitement