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本文用前瞻性研究方法,以HBsAg携带者家庭中阴性成员118人为暴露组,相同条件的阴性户109人为对照,自1983年10月15日至1986年10月15日,每年在同一时间做血清学检测和传摇因素调查登记。暴露组观察251人年,对照组观察228人年,每年百人HBsAg阳转率分别为3.59％和1.75％(RR=2.05,AR=1.84)。HBsAg阳性者伴HBeAg或/和抗-HBc比单项HBsAg阳性者传染性强,接触者HBsAg阳转率分别为10.00～13.50％和5.88％。HBsAg阳性父母的子女HBsAg阳转率和其他阳性成员接触者的阳转率分别为13.51％和8.51％(RR=1.58),排除母(父)婴传播和血液两因素后,由剩余其他因素(指生活接触)所致阳转率为9.8％。
In this study, a prospective study of 118 HBsAg negative family members exposed group, the same conditions negative 109 as a control, from October 15, 1983 to October 15, 1986 at the same time each year to do serum School testing and prejudice factor investigation registration. In the exposed group, 251 people were observed, while in the control group, 228 people were observed. The HBsAg positive rate of one hundred people per year was 3.59% and 1.75% respectively (RR = 2.05, AR = 1.84). HBsAg positive with HBeAg or / and anti-HBc than HBsAg-positive single contagious, contact HBsAg positive rates were 10.00 ~ 13.50% and 5.88%. The HBsAg positive rate among children with HBsAg positive parents and 13.51% and 8.51% (8.51%) were positive for contact with other positive members (RR = 1.58). After excluding both mother and father’s spread of blood and blood, Refers to life contact) caused by positive conversion rate of 9.8%.