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目的 :观察冠状动脉 (冠脉 )无明显狭窄 (<5 0 % )而冠脉血流储备异常患者的铊 2 0 1(2 0 1T1)负荷心肌洗脱率。方法 :随机测定 2 3例冠脉造影示冠脉正常或狭窄 <5 0 %患者不同冠脉的血流储备值 ,并根据冠脉血流储备 (CFR)分为 2组 :A组为CFR≥ 2 .5 (正常对照组 ) ,包括 34支冠脉 ;B组为CFR <2 .5 (冠脉微循环异常组 ) ,包括 16支冠脉。 2 3例受试者分别行2 0 1Tl潘生丁负荷心肌显像检查 ,处理出靶心图后 ,计算两组局部室壁洗脱率。洗脱率 =(负荷态放射性计数 -延迟态放射性计数 ) /负荷态放射性计数× 10 0 %。另根据心电图正常与否将上述患者分为两组 :组Ⅰ 12例 ,心电图完全正常 ;组Ⅱ 11例 ,平时心电图存在非特异性ST T改变 [成组导联的T低平或倒置和 (或 )ST压低≥ 0 .5mV]。比较两组的室壁洗脱率。结果 :A组的室壁洗脱率高于B组[(4 8.91± 7.75 ) %∶(36 .11± 6 .80 ) % ,P <0 .0 1];心电图有ST T改变的 11例受试者的相应 13段室壁洗脱率下降 ,为 (39.2 5± 7.86 ) % ,低于心电图完全正常的 12例受试者的 36段室壁洗脱率 [(4 9.5 6± 7.31) % ,P <0 .0 1]。结论 :CFR下降及心电图异常患者其心肌洗脱率相应下降
OBJECTIVE: To observe the myocardial elution rate of thallium 201 (2 0 1T1) load in patients with coronary artery (coronary artery) stenosis (<50%) and abnormal coronary flow reserve. Methods: The blood flow reserve values of different coronary arteries in 23 normal coronary artery stenosis or <50% stenosis patients were randomly divided into 2 groups according to coronary flow reserve (CFR): group A was CFR≥ 2.5 (normal control group), including 34 coronary arteries; group B was CFR <2.5 (abnormal coronary microcirculation group), including 16 coronary arteries. Twenty-three subjects underwent 201Tl dipyridamole myocardial perfusion imaging, respectively. After the target heart map was processed, the elution rates of two groups of local wall were calculated. Elution rate = (load state radioactive count - delayed state radioactive count) / load state radioactive count × 10 0%. In addition, the above patients were divided into two groups according to whether the ECG was normal or not: 12 cases of group Ⅰ, the electrocardiogram was completely normal; 11 cases of group Ⅱ had nonspecific ST T changes in normal electrocardiogram [T low level or inversion and / ) ST depression ≥ 0 .5mV]. Wall elution rates were compared between the two groups. Results: The wall elution rate in group A was significantly higher than that in group B [(8.91 ± 7.75)% vs (36.11 ± 6.80)%, P <0.01] The elution rate of the corresponding thoracic wall of the 13 subjects was (39.2 5 ± 7.86)% lower than that of the 36 subjects completely euthanized by electrocardiogram (36.56 ± 7.31) %, P <0 .0 1]. Conclusion: The decline of myocardial edema rate in patients with abnormal CFR and ECG abnormalities decreased accordingly