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目的 :探讨胃癌浆膜浸出的对策。方法 :对 10 0例进展期浸出浆膜面积 3～ 5cm2 ,并给予“治愈性”切除的胃癌患者 ,分为术中注药组及对照组各 5 0例。术中用药CDDP 80～ 10 0mg/m2 ,术后两组均随访 3年、5年。结果 :注药组与对照组 3年、5年生存率分别为 40 % (2 0 / 5 0 ) ,2 0 % (10 / 5 0 ) ;2 6 % (13/ 5 0 ) ,6 % (3/ 5 0 ) (P <0 .0 5 )。结论 :注药组 3年 5年生存率明显优于对照组 ,且与淋巴结转移与否无明显相关因素 (P >0 .0 5 )。
Objective: To explore the strategy of gastric mucosal leaching. Methods: One hundred and fifty cases of gastric cancer with leaching serosal area of 3 ~ 5cm2 and “curative” resection were divided into two groups, 50 cases in each group and 50 cases in control group. Intraoperative medication CDDP 80 ~ 100mg / m2, postoperative two groups were followed up for 3 years, 5 years. Results: The three-year and five-year survival rates of the injected group and the control group were 40% (20/50), 20% (10/50), 26% (13/50), 6% 3/5 0) (P <0. 05). Conclusion: The 3-year 5-year survival rate of the injected group is obviously better than that of the control group, and there is no significant correlation with the lymph node metastasis (P> 0.05).