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作者报告83例混合型胶质细胞瘤的临床诊治经验.本组44例肿瘤为Ⅰ或Ⅱ级;39例为Ⅲ或Ⅳ级.39例瘤组织由相等量的少枝胶质细胞与星形细胞两种胶质细胞成分构成;32例其成分以少枝胶质细胞为主;另12例肿瘤主要成分为星形细胞.均采取手术治疗或术后放疗.随访调查表明,术后平均生存时间为7.5年,而5,10和15年生存率分别为51%,31%和18%.此生存质量与患者年龄、肿瘤位置、大小及手术切除范围等因素有关.作者并观察到具有少枝胶质细胞成分为主的肿瘤易侵入多脑叶、基底节或丘脑区,且这类患者预后不良.
The authors report 83 cases of mixed glioblastoma clinical diagnosis and treatment experience. The group of 44 cases of tumor grade Ⅰ or Ⅱ; 39 cases were Ⅲ or Ⅳ grade. Thirty-nine tumor tissues consisted of two glial cells with equal amount of glial cells and astrocytes. Thirty-two glioma cells were mainly composed of less glia cells. The other 12 tumors were mainly composed of astrocytes. All were treated with surgery or postoperative radiotherapy. Follow-up survey showed that the average postoperative survival time was 7.5 years, while the 5, 10 and 15-year survival rates were 51%, 31% and 18% respectively. This quality of life and patient age, tumor location, size and surgical resection range and other factors. The authors also observed that tumors with less glial cells tend to invade into the lobes of multiple lobes, basal ganglia or thalamic regions, and that these patients have a poor prognosis.