冠状动脉内支架虽然可通过其机械作用阻止血管成形术后血管的弹性回缩 ,扩大管腔 ,即影响血管的重构来预防再狭窄。但支架对血管壁的损伤、异物的炎性反应、支架对血管长期牵拉作用等可导致血管平滑肌细胞的反应性增殖和内膜增生。一旦内膜增生超过支架扩张给予血管腔的补偿 , Coronary stent can prevent restenosis though its mechanical function can prevent the elastic retraction of blood vessels after angioplasty and enlarge the lumen, which affects the remodeling of blood vessels. However, the stent on the vessel wall injury, foreign body inflammatory response, stent long-term vascular pull the role of vascular smooth muscle cells can lead to reactive proliferation and intimal hyperplasia. Once the intimal hyperplasia exceeds the stent dilation to give compensation to the vessel lumen,