皮质纹状体脊髓变性 ,又称亚急性海绵状脑病 ,是由可传递因子引起的罕见的中枢神经系统变性病。本病为散发病例 ,死亡率极高。我院发现两例报告如下 :1　病例报告1 1　男性 ,6 5岁 ,农民。以精神异常 5 0天 ,行走不稳半月为主诉入院。查体 :神志清、精神紧张 ,恐惧 ,反应迟钝 , Corticosteroid spinal cord degeneration, also known as subacute spongiform encephalopathy, is a rare central nervous system degenerative disease caused by transmissible factors. The disease is sporadic cases, the mortality rate is high. Two cases of my hospital were reported as follows: 1 case report 1 1 male, 65 years old, farmer. To mental disorders 50 days, walking unsteady half of the main complaint hospitalization. Examination: Conscious, nervous, fear, unresponsive,