本文报告４例桥本病合并甲状腺癌，对桥本病表现、甲状腺癌类型及两者的过渡情况进行了形态学观察。结果发现：４例桥本病均可见滤泡上皮有增生，４例均合并有多灶性乳头状癌，癌组织与增生的异形上皮之间有移行现象。其中１例还合并有滤泡癌。本文结合文献资料从发病率、合并发生机理及临床病理特点对桥本病合并甲状腺癌进行了分析，认为乳头状癌与桥本病关系密切。 This paper reports on 4 cases of Hashimoto’s disease and thyroid cancer. The morphology of Hashimoto’s disease, the type of thyroid cancer and the transition of the two cases were observed by morphology. The results showed that: 4 cases of Hashimoto’s disease can be seen in the proliferation of follicular epithelium, 4 cases were combined with multi-focal papillary carcinoma, cancer tissue and hyperplasia between the heterogeneous epithelium migration phenomenon. One of them also had follicular carcinoma. In this paper, we analyzed the Hashimoto’s disease and thyroid cancer from the morbidity, merging mechanism and clinicopathological characteristics. We believe that papillary carcinoma is closely related to Hashimoto’s disease.