本文复习甲状腺功能低下症(以下简称甲低)的皮肤表现,并提出紫癜和瘀斑两种新的皮疹,并讨论了其发病机理。甲低或粘液水肿是一种系统性疾病,其面容表情呆板、肿胀、不活动和粗糙。由于粘液性非凹陷性水肿,在眼的下方形成明显的小囊,并累及眼睑、手、足和锁骨上凹。舌肥大、肿胀,其边缘可成扇形。口腔、咽和喉的粘膜常肿胀,引起声音嘶哑。由于水肿、贫血、胡萝卜素血症,皮肤的颜色呈苍白带黄色。胡萝卜素血症主要由于肝脏形成维生素A的能力减低,致使类胡萝卜色素沉积在角层内。皮肤冷(病人常诉感冷)、干燥和增厚,及由于皮脂和汗液分泌减少引起汗液中钠浓度增加。角化性 This article reviews the hypothyroidism (hereinafter referred to as hypothyroidism) of the skin manifestations and put forward two new purpura and ecchymosis rash, and discuss its pathogenesis. A hypothyroidism or mucoid edema is a systemic disorder with dull, swollen, inactive, and rough facial expressions. Due to mucinous non-pitting edema, a distinct sachet forms below the eye and involves the eyelids, hands, feet and clavicles. Tongue hypertrophy, swelling, the edge can be fanned. Oral, pharyngeal and laryngeal mucosa often swell, causing hoarseness. Due to edema, anemia, carotenoid blood, pale skin with yellow color. Carotenemia is mainly due to the reduced ability of the liver to form vitamin A, resulting in the deposition of carotenoids within the horn. Cold skin (patients often complain of cold), dryness and thickening, and increased sodium concentration in sweat due to decreased sebum and sweat secretion. Keratosis