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乙型肝炎病毒(HBV)感染除造成肝脏损伤外,还可通过免疫机制损伤肾脏,导致乙肝病毒相关性肾炎。以往的研究多限于从已确诊的肾小球肾炎推断其与HBV感染的关系。而对乙型肝炎病人肾脏损伤状况研究较少。为探索HBV持续感染对慢性乙型肝炎(CBH)、乙型肝炎后肝硬化(LC)病人肾脏影响,并较早地发现肾脏损伤,我们采用放射免疫法定量检测了CBH、LC病人尿微量白蛋白。现将结果报告如下。
Hepatitis B virus (HBV) infection in addition to causing liver damage, but also damage the kidneys through immune mechanisms, leading to hepatitis B virus-associated nephritis. Previous studies have mostly limited to inferring the relationship with HBV infection from diagnosed glomerulonephritis. However, there are few studies on the status of renal injury in hepatitis B patients. To investigate the effect of persistent HBV infection on the kidneys of patients with chronic hepatitis B (CBH) and post-hepatitis B cirrhosis (LC) and to detect kidney damage earlier, we used radioimmunoassay to quantify urinary microalbuminuria in CBH and LC patients protein. The results reported below.