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铝已被认为与透析性痴呆和Alzheimer氏病(早老性痴呆)的发病有关。神经原纤维球结中铝的浓集是Alzheimer氏病的组织学标志。食物及药物均为铝的来源,减少铝的摄入水平,可以降低痴呆的发病率。有关Alzheime病病因的另一假说是不明原因的血—脑屏障(BBB)功能异常,导致内源性影响行为活动的物质(如肽类)或神经毒素(如铝)进入脑内。作者的研究证实铝可改变BBB对碘处理
Aluminum has been considered to be associated with the development of dialysis dementia and Alzheimer’s disease (Alzheimer’s disease). The concentration of aluminum in the neurofibrillary tangles is a hallmark of Alzheimer’s disease. Food and medicine are sources of aluminum, reducing the level of aluminum intake, can reduce the incidence of dementia. Another hypothesis about the etiology of Alzheime disease is an unexplained dysfunction of the blood-brain barrier (BBB), leading to substances that endogenously affect behavioral activity such as peptides or neurotoxins such as aluminum into the brain. Authors’ studies confirm that aluminum can alter BBB treatment of iodine