离子选择性微电极作为测量生物细胞内外及微量试样中离子活度的新型工具而迅速应用在生物学、医学及其他各学科中。微电极可直接插入活体组织细胞中监测离子活度的变化,研究许多生理、生化、病理现象及机制,这是其他仪器分析方法所不能胜任的。自五十年代以来,pH玻璃微电极及钠、钾离子敏感性玻璃微电极不断发展,并在生物学中有着 Ion-selective microelectrodes are rapidly used in biology, medicine and other disciplines as a new tool to measure ion activity in biological cells both in vitro and in micrograms. Microelectrodes can be inserted directly into living tissue cells to monitor changes in ion activity and to study many physiological, biochemical, pathological phenomena and mechanisms that are beyond the capabilities of other instrumental methods. Since the 1950s, pH glass microelectrodes and sodium and potassium ion-sensitive glass microelectrodes have been developed and have been used in biology