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目的 观察中药清毒益气汤对于子宫颈高危型人乳头瘤病毒(HR-HPV)感染的治疗效果,为宫颈癌治疗提供有效的依据.方法 选取该院2015年9月-2017年2月收治的128例HR-HPV DNA核酸定量检测阳性患者作为研究对象,根据随机对照原则分为观察组(予自拟中药“清毒益气汤”治疗,64例)与对照组(予以重组人干扰素α-2b阴道泡腾胶囊治疗,64例).治疗2个月后停药,停药1个月后进行HR-HPV DNA核酸定量检测,观察疗效及预后相关指标.结果 观察组显效率53.13％,HR-HPV DNA转阴率为46.88％,治愈时间(7.21±1.00)周,未见预后不良者;与对照组比较,观察组显效率、转阴率显著升高;其余指标均降低,差异有统计学意义(均P＜0.05).结论 中药清毒益气汤治疗子宫颈高危型人乳头瘤病毒感染疗效佳,预后较好.“,”Objective To observe the curative effect of Qingduyiqi decoction in treatment of high-risk human papillomavirus (HR-HPV) infection,provide an effective basis for treatment of cervical cancer.Methods A total of 128 patients with positive HR-HPV DNA treated in the hospital from September 2015 to February 2017 were selected and randomly divided into observation group and control group,64 patients in each group.The patients in observation group were treated by Qingduyiqi decoction,and the patients in control group were treated by recombinant human interferon α-2b vaginal effervesce capsule.The treatment lasted for two months.At one month after drug withdrawal,HR-HPV DNA quantitative determination was performed,the curative effect and related indexes of prognosis were observed.Results The obvious effective rate in observation group was 53.13％,the negative conversion ratio of HR-HPV DNA was 46.88％,the cure time was (7.21 ± 1.00) weeks,the prognosis was good.Compared with control group,the obvious effective rate and negative conversion ratio in observation group increased significantly,the other indexes decreased significantly,there were statistically significant differences (all P＜0.05).Conclusion The curative effect of Qingduyiqi decoction in treatment of HR-HPV infection is good,and the prognosis is also good.