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目的与方法：为了了解高原地区消化性溃疡流行病学特征，本文分析了格尔木地区经内镜证实的消化性溃疡666例（DU349例；GU270例、CU47例）的性别、年龄及年龄分布、每月检出率、季度检出率及近10年的年检出率和常见并发症的发生率；结果：溃疡病的平均年龄为34．43±12．32岁，其中DU、GU和CU的平均年龄分别为32．72±11．13岁、36．53±12．98岁和38．41±12．96岁；DU／GU为1．29：1，溃疡病男女之比为6．09：1，其中OU、GU和CU男女之比分别为12.22：1、4.50：1和5.71：1溃疡的检出率以12月份最高，第四季度明显高于其它季度（P<1．01），进一步分析表明仅DU的检出率第四季度明显高于其它季度（P＜0．01）；资料还显示近10年来溃疡病的年检出率有逐渐增高的趋势，溃疡病常见的并发症的发生率出血、穿孔和幽门梗阻分别占16．82％、11．26％和3．15％；结论：结果表明高原地区溃疡病发病年龄较内地年轻，DU的检出率以第四季度最高，穿孔的发生率高原地区明显高于内地。
Objectives and Methods: To understand the epidemiological characteristics of peptic ulcer disease in the plateau region, we analyzed the gender, age and age distribution of 666 peptic ulcer patients (DU349 cases; GU270 cases and CU47 cases) confirmed by endoscopy in Golmud. Month detection rate and quarterly detection rate and the annual detection rate of 10 years and the incidence of common complications; Results: The average age of ulcer disease was 34.43 ± 12.32 years, of which DU, GU and CU The average age were 32.72 ± 11.13 years, 36.53 ± 12.98 years and 38.41 ± 12.96 years, respectively. The DU / GU was 1.29: 1, the ratio of male to female in ulcer disease was 6.09 : 1. The detection rates of ulcers in OU, GU and CU were 12.22: 1, 4.50: 1 and 5.71: 1, respectively, the highest in December and the fourth quarter were significantly higher than the other quarters (P <1.01) , Further analysis showed that only the detection rate of DU was significantly higher than the other quarters in the fourth quarter (P <0.01). The data also showed that the annual detection rate of ulcer disease tended to increase gradually. The common complication of ulcer disease The incidence of bleeding, perforation and pyloric obstruction accounted for 16.82%, 11.26% and 3.15% respectively. Conclusion: The results Age of onset of ulcer disease out at high altitude than younger mainland, the detection rate of DU in the fourth quarter, the highest rate of perforation of the original area was significantly higher than the mainland.