目的探讨长春瑞滨联合顺铂治疗晚期非小细胞肺癌的近期疗效及其毒副反应。方法按入选标准选择2005年10月12日至2006年10月6日月我科收住的晚期非小细胞肺癌56例进行长春瑞滨联合顺铂治疗。结果治疗有效率为52.4%,无严重并发症发生。结论长春瑞滨联合顺铂治疗治疗非小细胞肺癌是安全有效的一种手段,具有一定的临床应用价值。 Objective To investigate the short-term curative effect and toxicity of vinorelbine plus cisplatin in the treatment of advanced non-small cell lung cancer. Methods According to the inclusion criteria, 56 patients with advanced non-small cell lung cancer admitted to our department from October 12, 2005 to October 6, 2006 were treated with vinorelbine plus cisplatin. Results The effective rate of treatment was 52.4%, no serious complications occurred. Conclusion The combination of vinorelbine and cisplatin in the treatment of non-small cell lung cancer is a safe and effective method and has certain clinical value.