为了掌握绝经后出血（ＰＭＢ）病变性质的临床特征，以利于正确的诊断，对５１２例ＰＭＢ患者进行宫颈刮片、宫颈活体病检和Ｂ超后行分段诊刮术等。结果：年龄越大（＞６０岁）、绝经年限越长（≥６年）、间断性、不规则出血或出血时间越长（≥７天）、宫腔深度越长（≥６５ｃｍ）、子宫内膜越厚（≥７ｍｍ），其恶性肿瘤的可能性越大。结果说明：ＰＭＢ病因复杂，是生殖道恶性肿瘤的一个信号，要作全面检查，积极寻找病因，及时正确地治疗。 In order to grasp the clinical characteristics of the pathological features of postmenopausal bleeding (PMB), in order to facilitate the correct diagnosis, 512 cases of PMB patients with cervical smears, cervical biopsy and B-line sub-curettage and so on. Results: The older (> 60 years old), the longer the menopause (≥ 6 years), the longer the intermittent, irregular bleeding or bleeding (≥7 days), the longer the uterine cavity (≥65cm) The thicker the endometrium (≥7mm), the greater the likelihood of its malignancy. The results show that: PMB etiology is complex, is a signal of genital tract malignancy, to make a comprehensive examination, and actively look for the cause, timely and correct treatment.