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肺部慢性炎症是慢性阻塞性肺疾病(COPD)的特征。瘦素(leptin)是一种多效性细胞因子且被认为在大量炎症应答中起作用。最近研究显示肺部存在瘦素受体。本研究目的是确定在COPD患者诱导排痰中是否存在瘦素及瘦素与其它炎症标志有无联系。方法研究对象选择14例中度至重度正常体重
Chronic lung inflammation is a characteristic of chronic obstructive pulmonary disease (COPD). Leptin is a pleiotropic cytokine and is thought to play a role in a number of inflammatory responses. Recent studies have shown the presence of leptin receptors in the lungs. The aim of this study was to determine if leptin and leptin were involved in induction of sputum aspirates in COPD patients with or without other inflammatory markers. Methods Subjects were selected from 14 patients with moderate to severe normal weight