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我们自1993年3月至1993年10月期间,在辨证应用中药的基础上,使用抗乙肝免疫核糖核酸(iRNA)治疗慢性乙型肝炎31例,取得比较满意的近期效果,现小结如下: 临床资料:31例患者全部为住院病人,属于单纯性慢性乙肝患者。其中慢性迁延性肝炎10例,慢性活动性肝炎21例;男性18例,女性13例;年龄最小14岁,最大61岁;病史最短8个月,最长25年。治疗前后均检测乙肝三系(ELISA法)、HBV—DNA(斑点杂交法)、肝功能等,以做自身前后对照观察HBsAg、HBeAg、抗-HBc、HBV—DNA及ALT的变化情况。
We from March 1993 to October 1993 period, based on traditional Chinese medicine dialectical use of anti-hepatitis B immune RNA (iRNA) treatment of chronic hepatitis B in 31 cases, and achieved satisfactory results in the near future, are summarized as follows: Clinical Data: All 31 patients were inpatients, belonging to simple chronic hepatitis B patients. Including chronic persistent hepatitis in 10 cases, chronic active hepatitis in 21 cases; 18 males and 13 females; the youngest 14 years old, maximum 61 years old; the shortest history of 8 months, up to 25 years. The changes of HBsAg, HBeAg, anti-HBc, HBV-DNA and ALT were observed before and after treatment by ELISA, HBV-DNA (dot blot hybridization) and liver function.